non-canonical inhibition of dna damage-dependent ubiquitination by otub1
The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. This gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. Fine Tuning Of Dna Damage Dependent Ubiquitination By Otub2 Supports The Dna Repair Pathway Choice Semantic Scholar Mutations in this gene are associated with a variety of.